ea0065op5.4 | Reproductive Endocrinology and Biology | SFEBES2019
Phylactou Maria
, Abbara Ali
, Al-Memar Maya
, Eng Pei Chia
, Comninos Alexander N
, Izzi-Engbeaya Chioma
, Clarke Sophie A
, Mills Edouard
, Nadir Rans
, Sykes Mark
, Pacuszka Ewa
, Yang Lisa
, Fourie Hanine
, Bech Paul
, Kelsey Tom W
, Bourne Tom
, Dhillo Waljit S
Background: Placentation (invasion of the placenta into the maternal endometrium) is hypothesised to be critical for healthy placental function and is abnormal in two thirds of miscarriages. Kisspeptin has emerged as a putative regulator of physiological placentation; it is highly expressed in placental syncytiotrophoblasts and could play an important paracrine role in the regulation of placentation. Circulating kisspeptin levels are considerably raised during healthy pregnanc...